Name: Cheese Tortellini Pepperoni Pizza Casserole
Prep time: 10 min
Cook time: 25 min
Total time: 35 min
Cuisine: American
Ingredients: 1 package (9 oz) cheese tortellini; 1 cup marinara sauce; 1/2 cup pizza sauce; 1 1/2 cups shredded mozzarella cheese; 1/2 cup sliced pepperoni; 1/2 teaspoon dried oregano; 1/2 teaspoon garlic powder; 1/4 teaspoon red pepper flakes (optional); Fresh basil (optional, for garnish)

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A warm, hearty, and Cheese Tortellini Pepperoni Pizza Casserole that brings together the comfort of pasta and the irresistible flavors of pizza. I love how the tender cheese-filled tortellini gets baked in a rich tomato sauce, topped with plenty of gooey melted mozzarella, and finished with savory pepperoni slices. It’s the perfect weeknight dinner when I want something easy, filling, and full of flavor.

Cheese Tortellini Pepperoni Pizza Casserole

Ingredients

(Here's a tip: Check out the full list of ingredients and measurements in the recipe card below.)

1 package cheese tortellini (about 9 oz)

1 cup marinara sauce

½ cup pizza sauce

1 ½ cups shredded mozzarella cheese

½ cup sliced pepperoni

½ teaspoon dried oregano

½ teaspoon garlic powder

¼ teaspoon red pepper flakes (optional)

Fresh basil (optional, for garnish)

Directions

I preheat my oven to 375°F (190°C).

I cook the cheese tortellini according to the package instructions, then drain and set it aside.

In a large mixing bowl, I combine the marinara sauce and pizza sauce, then stir in the garlic powder, oregano, and red pepper flakes (if I’m using them).

I add the cooked tortellini to the sauce mixture and stir gently so each piece is coated.

I transfer the saucy tortellini into a greased 9x9-inch baking dish.

I top it with shredded mozzarella cheese and arrange the pepperoni slices evenly over the top.

I bake it for 20–25 minutes, until the cheese is melted and bubbly.

I garnish with fresh basil before serving hot.

Servings and timing

This recipe makes 4 servings.

Prep Time: 10 minutes

Cooking Time: 25 minutes

Total Time: 35 minutes

Calories: About 400 kcal per serving

Variations

I sometimes swap the pepperoni for cooked sausage, bacon, or even diced ham for a different flavor. For a veggie twist, I like to add sautéed mushrooms, bell peppers, or spinach. I can also make it extra cheesy by adding Parmesan or provolone along with the mozzarella. If I want a little kick, I use spicy pepperoni or add more red pepper flakes.

Storage/Reheating

I store leftovers in an airtight container in the refrigerator for up to 3 days. When I reheat, I cover the dish with foil and warm it in a 350°F oven until hot, or I microwave individual portions. If it seems a little dry, I add a splash of marinara sauce before reheating to bring back the moisture.

FAQs

Can I use frozen tortellini instead of fresh?

Yes, I just make sure to cook it according to the package directions before adding it to the casserole.

Can I prepare this ahead of time?

I often assemble the casserole earlier in the day, cover it, and refrigerate it. When I’m ready to bake, I add about 5 extra minutes to the cooking time.

Can I make it vegetarian?

Absolutely. I simply leave out the pepperoni or replace it with vegetarian pepperoni or extra vegetables.

What’s the best cheese for this recipe?

I like mozzarella for its meltability, but I sometimes mix in provolone, Monterey Jack, or even a bit of cheddar for more flavor.

Can I freeze the casserole?

Yes. I let it cool completely, wrap it tightly, and freeze it for up to 2 months. I thaw it overnight in the fridge before reheating.

Conclusion

I find this cheese tortellini pepperoni pizza casserole to be one of those meals that’s just as fun to make as it is to eat. It’s cheesy, comforting, and packed with flavor, making it perfect for family dinners or casual get-togethers. With its quick prep and versatile variations, it’s a recipe I can come back to again and again when I’m craving something hearty and satisfying.

Recipe:

Cheese Tortellini Pepperoni Pizza Casserole

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Author: Cheryl
Total Time: 35 minutes
Yield: 4 servings
Diet: Halal

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Description

A warm, hearty casserole that combines tender cheese-filled tortellini with rich marinara and pizza sauces, gooey mozzarella, and savory pepperoni, baked to bubbly perfection for the ultimate comfort food fusion of pasta and pizza.

Instructions

Preheat oven to 375°F (190°C).
Cook cheese tortellini according to package directions, then drain and set aside.
In a large mixing bowl, combine marinara sauce, pizza sauce, garlic powder, oregano, and red pepper flakes (if using).
Add cooked tortellini to the sauce mixture and gently stir to coat.
Transfer the mixture to a greased 9x9-inch baking dish.
Top with shredded mozzarella cheese and arrange pepperoni slices evenly on top.
Bake for 20–25 minutes, until cheese is melted and bubbly.
Garnish with fresh basil and serve hot.